Dendritic Cells and Virus Infection

Dendritic Cells and Virus Infection

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Dendritic cells are vital to induce potent anti-viral immune responses. It will become clear to the reader that dendritic cells often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and on the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes where they infect their prime target.... such failure is a result of ignorance. More likely, HPV-specific priming of the immune system has taken place, as witnessed by the frequent detection of HPV- specific immunity in patients with HPV-positive cervical lesions (see above), but this response is unable ... (Zwaveling et al. 2002). In severe cases, breaching of immunosuppressive mechanisms may even require a aquot;hard resetaquot; of the T cell immune system, for Interplay Between Human Papillomaviruses and Dendritic Cells 229.

Title:Dendritic Cells and Virus Infection
Author: Alexander Steinkasserer
Publisher:Springer Science & Business Media - 2003-04-23

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